ERK1/2 anticorps

N° du produit ABIN1734127

Cet anticorps Lapin Polyclonal détecte spécifiquement ERK1/2 dans WB. Il présente une réactivité envers Humain, Souris, Poulet, Xenopus laevis, Mammifères et Drosophila melanogaster.

Aperçu rapide pour ERK1/2 anticorps (ABIN1734127)

Antigène: ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))

Reactivité: Humain, Souris, Poulet, Xenopus laevis, Mammifères, Drosophila melanogaster

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERK1/2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ERK1/2 anticorps

Specificité: Reacts with human Erk1 and Erk2. Cross-reacts with mouse, rat, chicken, sheep, bovine, drosophila and xenopus protein.

Purification: Serum

Immunogène: 35 amino acid synthetic peptide corresponding to ERK1 conjugated to KLH.

Isotype: IgG

Information d'application

Indications d'application: Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
WB1:5000

Positive control: HeLa cell

Restrictions: For Research Use only

Stockage

Conseil sur la manipulation: Dilute in PBS or medium which is identical to that used in the assay system.

Stock: 4 °C/-20 °C

Stockage commentaire: Short term storage at+4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt.

Date de péremption: 6 months

Détails sur ERK1/2

Antigène: ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))

Autre désignation: Erk1 + Erk2

Sujet: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors.

Mitogen-activated protein kinase 3 & Mitogen-activated protein kinase 1 Extracellular signal-regulated kinase 1 & Extracellular signal-regulated kinase 3 ERK-1 & ERK-2 Gene name: MAPK3, MAPK1

UniProt: P27361, P28482